Synthesis and Structural Analysis of Ammonium Orotate Hydrate Crystal

Abstract

Single crystals of the title molecular salt, NH4 +. C5H3N2O4 ‒ . H2O, were isolated from the reaction of orotic acid, Dysprosium (III) Nitrate in a 1:1 molar ratio in 5 ml water 25% ammonia solution by hydrothermal reaction at 120oC for 3 days. In the crystal, the cations and anions are positioned alternately along an infinite helical chain and linked together through N---H...O hydrogen bonds between carboxylate oxygen and carbonyl oxygen of orotate ion. The water molecules of crystallization link the chains into (101) bilayers, with the cations organized in an isotactic manner.